Michelle L. Churchman

This paper identifies a chromatin-altered subtype of urothelial carcinoma defined by SWI/SNF alterations, showing it is sensitive to HDAC inhibition and immunotherapy.

This paper identifies biologically distinct transcriptomic and proteomic patterns of ADC and immunotherapy targets in urothelial carcinoma, linking them to histologic and molecular subtypes for precision therapy.

The paper identifies microbiome markers in primary colorectal cancer tumors that predict distant metastasis risk using cohort data and molecular techniques.

This study examines epigenetic, microbiome, and immune differences in early-onset colorectal cancer (EOCRC) compared to average-onset CRC, finding accelerated epigenetic aging and stronger immune-microbe correlations in EOCRC.

This study identifies Candida albicans colonization in colorectal tumors as a factor linked to reduced survival and impaired radiation response.

RIGATonI identifies genomic alterations in tumors affecting lymphocyte infiltration using machine learning and integrates immune phenotype and function predictions.

The paper introduces MEGA, a tool to identify cancer-associated microbes using RNA-seq data from the ORIEN dataset, leveraging graph attention networks and microbial community information.