Author

Lara Dötsch

TU Dortmund UniversityORCID 0000-0001-8100-5636Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra Brause· 1 shared Belén LucasiD· 1 shared Brenda Arlene SchulmaniD· 1 shared Ciriana OrabonaiD· 1 shared Daniel C. ScottiD· 1 shared Elisabeth Hennes· 1 shared Georg E. WinteriD· 1 shared Hana ImrichováiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alexandra Brause

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1 paper

Recent·Most cited

Cell BiologyNature ChemistryPeer-reviewedJan 7, 2026

Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3

Elisabeth Hennes, Belén Lucas, Natalie S. Scholes…·Herbert Waldmann

The paper identifies iDegs, which enhance IDO1 degradation via the native CRL2KLHDC3 pathway, reducing kynurenine formation and offering new therapeutic potential for cancer.

18 citationstop 1%

humanproteomics

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