Author

Ciriana Orabona

University of PerugiaORCID 0000-0003-3113-0572Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexandra Brause· 1 shared Antonio MacchiaruloiD· 1 shared Belén LucasiD· 1 shared Brenda Arlene SchulmaniD· 1 shared Claudia VolpiiD· 1 shared Daniel C. ScottiD· 1 shared Eleonora PanfiliiD· 1 shared Elisa BianconiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

Alexandra Brause

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2 papers

Recent·Most cited

Cell BiologyNature ChemistryPeer-reviewedJan 7, 2026

Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3

Elisabeth Hennes, Belén Lucas, Natalie S. Scholes…·Herbert Waldmann

The paper identifies iDegs, which enhance IDO1 degradation via the native CRL2KLHDC3 pathway, reducing kynurenine formation and offering new therapeutic potential for cancer.

18 citationstop 1%

humanproteomics

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Molecular BiologyeLifePeer-reviewedJun 30, 2023

A Back-Door Insights into the modulation of Src kinase activity by the polyamine spermidine

Sofia Rossini, Marco Gargaro, Giulia Scalisi…·Giada Mondanelli

This study identifies spermidine as a positive allosteric modulator of Src kinase by binding to a novel site on the SH2 domain, enhancing its interaction with IDO1.

13 citations

humanproteomics

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