Author
Memorial Sloan Kettering Cancer CenterORCID 0000-0001-8104-7166Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Hiroyuki Kojima, Charlotte R. Wayne, Luis F. Somarribas Patterson…·Ekaterina V. Vinogradova
In chronically stimulated human T cells, suppressed oxidative metabolism and nucleotide loss accompany MAP2K4 activation. Inhibiting MAP2K4 (with the MKK4/7 inhibitor BSJ-04-122) restored tumor-cell killing in vitro.
Charles Ng, Tak Shun Fung, Dayi Li…·Craig B. Thompson
This study shows that mitochondrial ATP production, induced by D-α-hydroxybutyrate, promotes T cell differentiation and function by regulating chromatin accessibility and gene expression.
Fei Yi, Tal Cohen, Natalie Zimmerman…·Christopher Austin Klebanoff
This study identifies FASLG expression patterns and shows that FAS-L/FAS auto-regulation governs CAR-T and CAR-NK cell persistence, enhancing antitumor efficacy when FAS is inhibited.