Author

Luca Ermini

Luxembourg Institute of HealthORCID 0000-0001-8109-6021Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Anaïs OudiniD· 2 shared Anna GolebiewskaiD· 2 shared Anuja LipsaiD· 2 shared Bakhtiyor NosiroviD· 2 shared Eliane KleiniD· 2 shared Simone P. NiclouiD· 2 shared Alexander PutraiD· 1 shared Ann‐Christin HauiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersCancer Biology

Anaïs OudinORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 9, 2025

Integrative multi-omics combined with functional pharmacological profiling in patient-derived organoids identifies personalized therapeutic vulnerabilities of adult high-grade gliomas

Luca Ermini, Anuja Lipsa, Ann‐Christin Hau…·Anna Golebiewska

This study integrates multi-omics and functional drug screening in patient-derived organoids to identify personalized therapeutic vulnerabilities in adult high-grade gliomas, finding distinct drug responses in IDH1 mutant and MYCN-amplified tumors.

5 citations

humanbulk RNA-seq

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Cancer BiologyMolecular OncologyPeer-reviewedNov 13, 2024

T-Cell-Mediated Killing in Glioblastoma Organoids induced by Adenoviral Delivery of the CIITA Transgene

Ilaria Salvato, Eliane Klein, Aurélie Poli…·Simone P. Niclou

This study shows that adenoviral delivery of CIITA enhances T-cell mediated killing of glioblastoma organoids, with some MHC-II-independent immune responses observed.

12 citations

humanorganoid / primary culture

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GenomicsGenome biologyPeer-reviewedSep 3, 2021

LeafGo: Leaf to Genome, a quick workflow to produce high-quality De novo genomes with Third Generation Sequencing technology

Patrick Driguez, Salim Bougouffa, Karen Carty…·Luca Ermini

LeafGo provides a rapid, cost-effective workflow for generating high-quality de novo plant genomes using third-generation sequencing technologies within seven days.

40 citations

plant (other)whole-genome sequencing

𝕏 PostBluesky