Patrick Driguez

The paper compares short- and long-read sequencing technologies in metagenomics, showing that longer short reads with optimal prep improve assembly and protein detection without needing more sequencing depth.

The paper presents a fully annotated reference genome from a Saudi individual using de novo assembly and AI-based annotation, making all data publicly available.

This study identifies daily transcriptomic rhythms in Schistosoma mansoni, revealing rhythmic gene expression patterns and their potential relevance to parasite survival and drug targets.

LeafGo provides a rapid, cost-effective workflow for generating high-quality de novo plant genomes using third-generation sequencing technologies within seven days.

This paper uses CRISPR/Cas9 to edit the acetylcholinesterase gene in Schistosoma mansoni eggs, resulting in reduced AChE activity and decreased granuloma size in mice.

This study uses CRISPR-Cas9 to induce deletions in the SULT-OR gene of Schistosoma mansoni, showing potential for oxamniquine resistance but limited mRNA knockdown due to low mutation frequency.

This paper demonstrates CRISPR/Cas9-based genome editing in Schistosoma mansoni, successfully mutating the omega-1 gene and reducing Th2 cytokine responses and granuloma formation.