Jamïlé Hazan

This study identifies vascular dysfunction as a key contributor to oxaliplatin-induced peripheral neuropathy in mice by showing increased vasoconstriction and hypoxia, which can be mitigated by vasodilators.

The paper shows that tubulin polyglutamylation regulates microtubule-severing enzymes in axon guidance, with TTLL6 and TTLL11 having distinct roles in zebrafish and mammalian neurons.