Ratnakar Tiwari

This study creates a longitudinal transcriptomic atlas of salt-induced hypertension in rats, identifying shared and organ-specific transcriptional changes and candidate therapeutics.

This study identifies endothelial PHD3 as a regulator of kidney repair after ischemia, showing its role in suppressing inflammation and fibrosis through HIF-dependent mechanisms.

This paper develops dual-ligand micelles for targeted nanocarrier delivery in acute kidney injury, showing enhanced accumulation in injured kidneys and reduced off-target distribution.

This study shows that inactivating PHD enzymes in endothelial cells after ischemic kidney injury promotes maladaptive repair through glycolysis and MCT4, which can be reversed by MCT4 inhibitors.

This study shows that inhibiting prolyl hydroxylases with DMOG impairs angiogenic competence of human vascular endothelial cells through metabolic reprogramming.