Matthew John Schipma

Binary-SPA improves cell type annotation in spatial transcriptomics by using a two-stage approach without requiring external reference data.

This paper introduces an antibody language model (AbLM) to accelerate IgG screening and design for broad-spectrum antiviral therapy, achieving higher precision in predicting variant-resistant antibodies.

This study shows that inactivating PHD enzymes in endothelial cells after ischemic kidney injury promotes maladaptive repair through glycolysis and MCT4, which can be reversed by MCT4 inhibitors.

This study shows that inhibiting prolyl hydroxylases with DMOG impairs angiogenic competence of human vascular endothelial cells through metabolic reprogramming.