Adele Williamson

The paper investigates how DNA ligases handle non-canonical base pairs in hachimoji DNA, finding that consecutive non-canonical bases at the 3-end reduce ligation efficiency.

The paper shows Lig E increases transformation of N. gonorrhoeae with nuclease-damaged extracellular DNA, suggesting a role in overcoming environmental DNA degradation.

This study investigates the role of Lig E in Neisseria gonorrhoeae biofilm and microcolony formation, showing it enhances extracellular DNA ligation and matrix strength.

The paper shows that Prochlorococcus marinus uses an ATP-dependent DNA ligase for DNA replication, challenging the established view that bacteria exclusively use NAD-dependent ligases.