Rose Marie Akiki

This study shows that HDAC5 in the prelimbic prefrontal cortex reduces context-associated cocaine seeking but not sucrose seeking, altering synaptic gene expression and excitatory/inhibitory balance.

This study shows that NPAS4 in the medial prefrontal cortex is required for chronic social defeat stress-induced anhedonia and dendritic spine loss, but not social avoidance or anxiety-like behavior.

This study shows NPAS4 regulates drug-cue associations and relapse-like behavior by controlling the activation balance between D1- and D2-MSNs in the nucleus accumbens.