Leila Nabulsi

Lifespan Normative Modeling of Brain Microstructure

This paper develops a lifespan normative model of brain white matter microstructure using diffusion MRI data from 54,583 individuals, enabling detection of microstructural deviations in diseases like Alzheimer's and 22q11.2 deletion syndrome.

Structural Brain Network Alterations in Relation to Treatment and Illness Severity in Bipolar Disorder

This study analyzes structural brain network changes in bipolar disorder, finding widespread connectivity disruptions linked to illness severity and medication use.

Along-Tract Microstructural Alterations Associated with Stimulant Misuse Localized using Diffusion MRI Tractometry

This study uses diffusion MRI tractometry to identify localized white matter microstructural changes associated with stimulant misuse, finding distinct patterns for amphetamine use compared to cocaine use.

Distributional and Centile Calibration of Diffusion Tensor Imaging Normative Models as Training Sample Sizes Increase to 40,000 Subjects

The paper examines how increasing training sample size improves the calibration of diffusion tensor imaging normative models using hierarchical Bayesian regression.

A Scalable Toolkit for Modeling 3D Surface-based Brain Geometry

The paper introduces a scalable toolkit for 3D surface-based brain analysis, demonstrating its utility in mapping subcortical shape variations across 21 international samples.

Deriving Mendelian Randomization-based Causal Networks of Brain Imaging Phenotypes and Bipolar Disorder

This study uses Mendelian Randomization to identify causal relationships between neuroimaging phenotypes and bipolar disorder, finding that white matter tract variations have larger causal effects on BD.

Multi-Site Statistical Mapping of Along-Tract Microstructural Abnormalities in Bipolar Disorder with Diffusion MRI Tractometry

This study maps microstructural abnormalities along white matter tracts in bipolar disorder using multisite diffusion MRI tractometry and identifies significant differences in fractional anisotropy between BD patients and controls.

Along-Tract Statistical Mapping of Microstructural Abnormalities in Bipolar Disorder: A Pilot Study

This study uses diffusion MRI and BUAN to map microstructural differences in white matter tracts between bipolar disorder patients and controls, finding altered Fractional Anisotropy in specific pathways.

FiberNeat: Unsupervised White Matter Tract Filtering

FiberNeat filters false positive and implausible streamlines from tractograms using unsupervised methods, improving tract quality and tractometry.

Age and Sex Effects on Advanced White Matter Microstructure Measures in 15,628 Older Adults: A UK Biobank Study

This study examines age and sex effects on white matter microstructure in 15,628 older adults using dMRI models, finding that advanced models like TDF and NODDI detect these effects most sensitively.

Exogenous Sex Hormone Effects on Brain Microstructure in Women: A Diffusion MRI Study in the UK Biobank

This study examines how exogenous sex hormones affect white matter aging in postmenopausal women using diffusion MRI data from the UK Biobank, finding steeper aging trajectories in hormone therapy users.

Age-dependent genetic variants associated with longitudinal changes in brain structure across the lifespan

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.