Author

Jose David Aponte

University of CalgaryORCID 0000-0002-1608-8612Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:GWAS / association mapping· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Benedikt HallgrímssoniD· 3 shared Charles C. RosemaniD· 2 shared David C. KatziD· 2 shared James M. CheverudiD· 2 shared Ralph S. MarcucioiD· 2 shared Stephen A. MurrayiD· 2 shared Wei LiuiD· 2 shared Christopher J. PercivaliD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Benedikt HallgrímssonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Syndrome-informed phenotyping identifies a polygenic background for achondroplasia-like facial variation in the general population

Michiel Vanneste, Hanne Hoskens, Seppe Goovaerts, Harold S. Matthews, Jay Devine, Jose David Aponte, Joanne B. Cole, Mark D. Shriver, Mary L. Marazita, Seth Michael Weinberg, Susan Walsh, Stephen Richmond, Ophir D. Klein, Richard A. Spritz, Hilde Peeters, , Peter D. Claes

The paper identifies genomic loci associated with achondroplasia-like facial variation in the general population using a syndrome-informed phenotyping approach.

Nature Communications · Dec 2, 2024Peer-reviewedGenetics

Shapes and Genescapes: Mapping Multivariate Phenotype-Biological Process Associations for Craniofacial Shape

J. David Aponte, David C. Katz, Daniela Marta Roth, Marta Vidal‐García, Wei Liu, Fernando Andrade, Charles C. Roseman, Stephen A. Murray, James Cheverud, Daniel Graf, Ralph S. Marcucio, Benedikt Hallgrímsson

The paper develops a process-centered multivariate genotype-phenotype approach to analyze craniofacial shape variation in mice, linking gene sets to shape axes and predicting phenotypic effects beyond shape.

eLife · Nov 15, 2021Peer-reviewedGenomics

Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes

David C. Katz, Jose David Aponte, Wei Liu, Rebecca M. Green, Jessica Mayeux, K. Michael Pollard, Daniel Pomp, Steven C. Munger, Stephen A. Murray, Charles C. Roseman, Christopher J. Percival, James M. Cheverud, Ralph Marcucio, Benedikt Hallgrímsson

This study identifies 37 QTL for facial shape in DO mice, finding enrichment for genes involved in skeletal and facial development, despite small individual effects.

PLoS ONE · Jun 5, 2020Peer-reviewedGenetics