ImmunologybioRxivPreprint
VH-replacement shapes the antibody repertoire by targeting non-pairing heavy-chains
Harry N White, Peter Chovanec, Laura Biggins…·Anne E. Corcoran
The paper investigates VH-replacement in B-cell development, finding it targets non-pairing productive VDJ rearrangements to reshape the antibody repertoire.
DOI 10.1101/2025.04.07.647564