Author

Hongquan Zhang

Peking UniversityORCID 0000-0001-8193-0899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Chen‐Ying LiuiD· 1 shared Jing Zhang· 1 shared Jun ZhaniD· 1 shared Lei ZhangiD· 1 shared Miao YuiD· 1 shared Qianchen Li· 1 shared Weijie WuiD· 1 shared Wenjing WangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Chen‐Ying LiuORCID

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1 paper

Recent·Most cited

Cancer BiologyeLifePeer-reviewedMar 31, 2025

Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism

Weijie Wu, Miao Yu, Qianchen Li…·Hongquan Zhang

This study identifies FRMD8 as a regulator of ER levels in ER-positive breast cancer, showing it confers tamoxifen resistance through dual mechanisms involving transcriptional and post-translational regulation of ER.

DOI 10.7554/elife.101888.3

mousebulk RNA-seq

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