Author

Marek B. Körner

University Hospital LeipzigORCID 0000-0001-8221-8975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Nicole ScholziD· 3 shared Tobias LangenhaniD· 3 shared Achmed MrestaniiD· 2 shared Akhil VelluvaiD· 2 shared Antje GarteniD· 2 shared Diana Le DuciD· 2 shared Julia HentscheliD· 2 shared Linnaeus BundalianiD· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Nicole ScholzORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 16, 2023

Drosophila Bchs overexpression recapitulates human WDFY3 neurodevelopmental phenotypes with implications for glial cell involvement in altered head circumference

Marek B. Körner, Akhil Velluva, Linnaeus Bundalian…·Diana Le Duc

This study shows that overexpression of the Drosophila Bchs gene, an ortholog of human WDFY3, causes neural developmental issues in both neurons and glial cells, mirroring human neurodevelopmental disorders.

DOI 10.1101/2023.10.16.562295

Drosophilabulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 11, 2023

Intron retention of an adhesion GPCR generates single transmembrane-helix isoforms to enable 7TM-adhesion GPCR function

Anne Bormann, Marek B. Körner, Anne-Kristin Dahse…·Nicole Scholz

The paper shows that intron retention generates single transmembrane-helix isoforms of aGPCRs, enabling mechanosensory function through heteromerization with 7TM subunits.

3 citations

Drosophilamouse

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Genetic & Genomic MedicineScientific ReportsPeer-reviewedAug 5, 2022

Altered gene expression profiles impair the nervous system development in individuals with 15q13.3 microdeletion

Marek B. Körner, Akhil Velluva, Linnaeus Bundalian…·Diana Le Duc

The paper identifies altered gene expression patterns in 15q13.3 microdeletion carriers, showing dysregulation of genes involved in brain development and contributing to phenotypic variability.

6 citations

mousebulk RNA-seq

𝕏 PostBluesky