Author

Vera I. Wiersma

University of ZurichORCID 0000-0001-8223-4588Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Magdalini PolymenidouiD· 2 shared Marián Hruška-PlocháňiD· 2 shared Adriano AguzziiD· 1 shared Alexander LeitneriD· 1 shared Alexander van der BourgiD· 1 shared Alexandra Oertel· 1 shared Amedeo CaflischiD· 1 shared Andreas R. HierlemanniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Magdalini PolymenidouORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintOct 5, 2026

Monomeric TDP-43 binds GU-rich RNA via its NTD but only its oligomers block cryptic exon inclusion

Aurélie Zbinden, Izabela Smok, Flaminia Pellegrini…·Magdalini Polymenidou

This study shows that the NTD of TDP-43 binds UG-rich RNA on monomers, while oligomerization is essential for repressing cryptic exons.

DOI 10.64898/2026.10.01.755875

humanproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 10, 2023

Neuronal lipofuscinosis caused by Kufs disease/CLN4 DNAJC5 mutations but not by a CSPα/DNAJC5 deficiency

Santiago López-Begines, Ángela Lavado-Roldán, Cristina Mesa-Cruz…·Rafael Fernández‐Chacón

This study creates mouse models overexpressing mutant CSP/DNAJC5 and shows they develop neuronal lipofuscinosis and GRODs, while CSP/DNAJC5 deficiency does not.

1 citation

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 8, 2021

Human neural networks with sparse TDP-43 pathology reveal NPTX2 misregulation in ALS/FTLD

Marián Hruška-Plocháň, Katharina M. Betz, Silvia Ronchi…·Magdalini Polymenidou

The paper develops a human iPSC-derived neural model to study TDP-43 pathology, identifying NPTX2 misregulation as a key factor in ALS/FTLD neurotoxicity.

10 citations

𝕏 PostBluesky