Claire Marchal

The paper integrates 4D Nucleome data to analyze 3D genome structure and function in human cells, revealing chromatin domains, loops, and interactions, and showing how genetic variants affect genome folding.

The paper shows that glycolysis and lactate regulate histone H3K18 lactylation to control gene expression in retinal development and maturation.

The paper identifies interactions between NRL and RNA-binding proteins, including R-loops in retinal photoreceptors, revealing new roles for NRL in transcription and gene regulation.

This study uses Optical Replication Mapping to map human DNA replication initiation sites and finds that replication initiation is stochastic and not confined to specific origins.

HiCRes estimates and predicts HiC library resolution using mathematical concepts applied to human and mouse datasets.

This paper introduces a protocol and computational tools for genome-wide replication timing analysis using next-generation sequencing.