Author

Christopher Frederick Mugler

University of California, BerkeleyORCID 0000-0001-8258-1192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:yeast· 1

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Karsten WeisiD· 1 shared Leon Y ChaniD· 1 shared Pascal VallottoniD· 1 shared Stephanie HeinrichiD· 1 shared

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2018-2018 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperGenetics

Karsten WeisORCID

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1 paper

Recent·Most cited

GeneticseLifePeer-reviewedSep 7, 2018

Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability

Leon Y Chan, Christopher Frederick Mugler, Stephanie Heinrich…·Karsten Weis

The paper measures mRNA decay in yeast and finds translation initiation, not codon optimality or elongation, determines mRNA stability, with an average half-life of 4.8 minutes.

214 citationstop 2%

yeastbulk RNA-seq