Author

Pascal Vallotton

ETH ZurichORCID 0000-0002-4159-1447Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:yeast· 1

Frequent Co-Authors

Christopher Frederick MugleriD· 1 shared Karsten WeisiD· 1 shared Leon Y ChaniD· 1 shared Stephanie HeinrichiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperGenetics

Christopher Frederick MuglerORCID

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1 paper

Recent·Most cited

Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability

Leon Y Chan, Christopher Frederick Mugler, Stephanie Heinrich, Pascal Vallotton, Karsten Weis

The paper measures mRNA decay in yeast and finds translation initiation, not codon optimality or elongation, determines mRNA stability, with an average half-life of 4.8 minutes.

eLife · Sep 7, 2018Peer-reviewedGenetics