Marie MacLennan

The paper identifies mutational biases at germline regulatory sites, showing increased structural variants and insertions at transcription factor binding sites, with implications for evolution and disease.

This study shows Tex19.1 maintains acetylated SMC3 and sister chromatid cohesion in mouse oocytes, preventing aneuploidy.

This study identifies Tex19.1 and Ubr2 as regulators of meiotic DNA double strand break frequency in mouse spermatocytes, ensuring proper homologous chromosome pairing and meiotic progression.

This study shows that TEX19.1 restricts L1 retrotransposon mobilisation in mouse embryonic stem cells by promoting the degradation of L1-ORF1p.