Author

Abigail R. Mann

Institute of Genetics and CancerORCID 0000-0002-2510-7299Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3 Genetics· 1

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

Javier F. CáceresiD· 3 shared Dáša LongmaniD· 2 shared Ian R. AdamsiD· 2 shared Stuart AitkeniD· 2 shared Alberto Rodolfo KornblihttiD· 1 shared Ana Rio‐MachíniD· 1 shared Benjamin J. BlencoweiD· 1 shared Carmen Salvador‐PalomequeiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMolecular Biology

Javier F. CáceresORCID

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4 papers

Recent·Most cited

The moonlighting functions of SEC13 in nonsense-mediated mRNA decay and the regulation of ER stress

Laura Monaghan, Chetan F Srinath, Abigail R. Mann, Nila Roy Choudhury, Graeme R. Grimes, Dáša Longman, Javier F. Cáceres

This study identifies SEC13 as a novel NMD factor in mammalian cells and shows its role in regulating ER stress through the UPR pathway.

RNA · Sep 2, 2026Peer-reviewedMolecular Biology

A dual role for the RNA helicase DHX34 in NMDand pre-mRNA splicing and its function inhematopoietic differentiation

Nele Hug, Stuart Aitken, Dáša Longman, Michaela Raab, Hannah Armes, Abigail R. Mann, Ana Rio‐Machín, Jude Fitzgibbon, Kevin Rouault‐Pierre, Javier F. Cáceres

This study identifies DHX34 as a dual regulator of NMD and pre-mRNA splicing, showing its role in hematopoietic differentiation and disease.

RNA · Jun 29, 2022Peer-reviewedMolecular Biology

Slow transcriptional elongation causes embryonic lethality and perturbs kinetic coupling of long neural genes

Magdalena M. Maslon, Ulrich Braunschweig, Stuart Aitken, Abigail R. Mann, Fiona M. Kilanowski, Chris J. Hunter, Benjamin J. Blencowe, Alberto Rodolfo Kornblihtt, Ian R. Adams, Javier F. Cáceres

This study shows that slow RNAPII elongation causes embryonic lethality and disrupts splicing and gene expression in neural differentiation.

The EMBO Journal · Apr 15, 2019Peer-reviewedMolecular Biology

Tex19.1 Restricts LINE-1 Mobilisation in Mouse Embryonic Stem Cells

Marie MacLennan, Marta García-Cañadas, Judith Reichmann, Elena Khazina, Carmen Salvador‐Palomeque, Abigail R. Mann, Paula Peressini, Laura Sánchez, Christopher J. Playfoot, David Read, Chao-Chun Hung, Ragnhild Eskeland, Richard R. Meehan, Oliver Weichenrieder, Jose Luis Garcia-Perez, Ian R. Adams

This study shows that TEX19.1 restricts L1 retrotransposon mobilisation in mouse embryonic stem cells by promoting the degradation of L1-ORF1p.

bioRxiv · Feb 9, 2017 · PreprintGenetics