Shinji Mii

This study shows that locally produced C3 in cancer-associated fibroblasts, not circulating C3, determines immune checkpoint blockade efficacy by modulating myeloid cell infiltration.

The paper establishes a database of lung cancer mouse models to improve data comparison and translational relevance by aligning mouse mutations with human lung cancer mutations.

DeepCOLOR identifies cell-cell interactions by reconstructing spatial colocalization maps from single-cell and spatial transcriptomes in various tissues.