Author

Shadi Jafari

Linköping UniversityORCID 0000-0001-8271-5488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Organism:Drosophila· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Hua YaniD· 2 shared Mattias AleniusiD· 2 shared Björn GylemoiD· 1 shared Bogdan SieriebriennikoviD· 1 shared Colm E. NestoriD· 1 shared Dóra Goldmann· 1 shared Engla Haglund· 1 shared Ingela Johansson· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Hua YanORCID

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4 papers

Recent·Most cited

TRiXi: A Multi-Target Tandem Repeat-Based Method for Accurate Detection of X-Inactivation Skewing in Humans

Dóra Goldmann, Björn Gylemo, Maike Bensberg, Ingela Johansson, Svenja Löffert, Júlia Goldmann, Lisa Haglund, Magda Vítková, Janos Kondri, Sandra Hellberg, Engla Haglund, Shadi Jafari, Johnny Ludvigsson, Colm E. Nestor

TRiXi detects X-inactivation skewing in human DNA, revealing it as a common and stable epigenetic trait across multiple tissues and ages.

medRxiv · Nov 24, 2025 · PreprintGenetic & Genomic Medicine

Activity-dependent survival of odorant receptor neurons in ants

Bogdan Sieriebriennikov, Kayli R. Sieber, Olena Kolumba, Jakub Mlejnek, Shadi Jafari, Hua Yan

The paper shows that in ants, orco mutations cause ORN apoptosis, but some ORNs survive by expressing Ir genes, suggesting chemosensory receptors mediate activity-dependent survival.

bioRxiv · Oct 4, 2023 · PreprintDevelopmental Biology

Activity and stress during a critical period regulate olfactory sensory neuron differentiation

Shadi Jafari, Johan Henriksson, Hua Yan, Mattias Alenius

The paper shows that neuronal activity and stress during a critical period regulate olfactory receptor expression in Drosophila by modulating gene regulatory mechanisms.

PLoS Biology · Apr 1, 2021Peer-reviewedNeuroscience

A critical period terminates the differentiation of olfactory sensory neurons

Shadi Jafari, Mattias Alenius

The paper identifies a critical period in Drosophila olfactory sensory neuron differentiation that stabilizes odorant receptor expression through gene regulatory mechanisms similar to mammalian systems.

bioRxiv · Feb 12, 2020 · PreprintNeuroscience