Expression of immune checkpoint VISTA represents a differentiated state of cancer cells and plays a role in regulating actin cytoskeleton
Chen Wang, Yang Liu, Jing Li, Ying Cao
This study shows that high VISTA expression in cancer cells indicates a less malignant state and affects actin cytoskeleton, suggesting immune checkpoints may have non-immunological roles in cancer.
bioRxiv · Aug 26, 2026 · PreprintCancer Biology