Author

Megan C. Holmes

British Heart Foundation Centre for Cardiovascular ScienceORCID 0000-0001-8294-0642Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda Jane DrakeiD· 1 shared Céline GrenieriD· 1 shared Dawn E. W. LivingstoneiD· 1 shared Eamon FitzgeraldiD· 1 shared Hannah M. CostelloiD· 1 shared James P. BoardmaniD· 1 shared Jessica Ruth IvyiD· 1 shared Kevin StewartiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Amanda Jane DrakeORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintDec 11, 2024

Renal arterial dysfunction, impaired pressure natriuresis and salt-sensitivity in a mouse model of Cushing syndrome

Hannah M. Costello, Céline Grenier, Jessica Ruth Ivy…·Matthew A. Bailey

This study shows that Cushing Syndrome in mice causes impaired renal pressure natriuresis, altered blood pressure regulation, and salt-sensitivity.

1 citation

mouseexperimental assay

𝕏 PostBluesky

Developmental BiologyEpigenetics & ChromatinPeer-reviewedJun 30, 2021

Altered hypothalamic DNA methylation and stress-induced hyperactivity in a novel model of early life stress

Eamon Fitzgerald, Matthew C. Sinton, Sara Wernig-Zorc…·Amanda Jane Drake

This study develops a novel mouse model of early life stress and finds altered hypothalamic DNA methylation and stress-specific hyperactivity in adulthood.

19 citations

mouseDNA methylation

𝕏 PostBluesky