Amanda Jane Drake

This study develops a novel mouse model of early life stress and finds altered hypothalamic DNA methylation and stress-specific hyperactivity in adulthood.

This study shows early life stress impairs social function and increases AVP expression, which can be mitigated by an AVP receptor antagonist in animal models and correlates with emotional recognition in BPD patients.

The paper identifies FKBP5 epigenetic derepression by aging and stress as a driver of NF-kB-driven inflammation and cardiovascular risk through in vitro and cohort studies.

This study compares gene expression changes in rodent models of methyl donor deficiency with human NAFLD, finding limited similarity but shared inflammatory and fibrotic pathways.