Eamon Fitzgerald

This study identifies expression networks of MDD risk genes linked to astrocyte fatty acid metabolism and suicidal ideation, suggesting PPARA as a therapeutic target.

The paper defines a homeostatic inflammation signature in the placenta, creates a polygenic score, and shows its protective effects on cardiovascular and depressive outcomes using UK Biobank data.

The paper shows that microglial function influences how depression risk factors affect depression outcomes differently in females compared to males across the life course.

This study develops a novel mouse model of early life stress and finds altered hypothalamic DNA methylation and stress-specific hyperactivity in adulthood.

This study shows that primary cilia regulate direct versus indirect neurogenesis in the developing cerebral cortex, with Inpp5e mutations causing increased direct neurogenesis and layer V neuron overproduction.