Author

Heba Saadeh

University of JordanORCID 0000-0001-8294-6278Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Eiman I. AhmediD· 2 shared Jessica P RoelandsiD· 2 shared Wouter HendrickxiD· 2 shared Alex L. Nigg· 1 shared Andrea SacchettiiD· 1 shared Annemarie C. de Vries· 1 shared Bertille MontibusiD· 1 shared Christophe Michel RaynaudiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCancer Biology

Eiman I. AhmedORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 23, 2026

Inflammation-driven reprogramming of goblet cells underlies the onset of serrated adenomas in colon cancer

Mathijs P. Verhagen, Emily Middendorp Guerra, Rosalie Joosten…·Riccardo Fodde

The paper investigates how inflammation reprograms goblet cells into tumor-initiating cells in colon cancer using single-cell RNAseq and mutation spectrum analysis.

DOI 10.64898/2026.06.22.733748

mousescRNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintFeb 4, 2026

Methylation-Guided Stratification of Colorectal Cancer Reveals Immune Subtypes with Distinct Clinical Outcomes

Eiman I. Ahmed, Raghvendra Mall, Christophe Michel Raynaud…·Wouter Hendrickx

This study identifies immune subtypes of colorectal cancer using methylation patterns, linking them to distinct clinical outcomes and immune programs.

DOI 10.64898/2026.02.03.703457

humanDNA methylation

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedJul 1, 2020

Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing

Samuele M. Amante, Bertille Montibus, Michael Cowley…·Rebecca J. Oakey

The paper investigates how intragenic CpG islands (iCGIs) influence host gene pre-mRNA processing through transcriptional activity, showing a correlation between iCGI transcription and premature termination of host gene transcripts.

19 citations

humanDNA methylation

𝕏 PostBluesky