Michael Cowley

Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

This study generates Grb7 KO mice and shows Grb7 and Grb14 have minimal impact on fetal growth but Grb7 may promote kidney growth and subtly affects glucose metabolism in adults.

Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing

The paper investigates how intragenic CpG islands (iCGIs) influence host gene pre-mRNA processing through transcriptional activity, showing a correlation between iCGI transcription and premature termination of host gene transcripts.