Author

Rosalie Joosten

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Andrea SacchettiiD· 2 shared Mathijs P. VerhageniD· 2 shared Riccardo FoddeiD· 2 shared Alex L. Nigg· 1 shared Annemarie C. de Vries· 1 shared Coen Linn· 1 shared Eiman I. AhmediD· 1 shared Emily Middendorp Guerra· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Andrea SacchettiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Western-style diet-induced microbial shifts and inflammation reprogram c-Kit⁺ secretory cells into targets for tumor initiation

Sara Silva, Paola Procopio, Valeriya V. Zinina, Solveig Turss, Rafael R. Segura Muñoz, Seyram Segbefia, Sena Bae, Lior Lobel, Luigi L. Nardella, Andrea Sacchetti, Rosalie Joosten, Coen Linn, Susanna Plugge, Mathijs P. Verhagen, Fatma Aktuna, , Mark R. Schmitt

This study shows that a Western-style diet reprograms c-Kit⁺ secretory cells into tumor-initiating cells via microbial shifts and inflammation.

bioRxiv · Jul 19, 2026 · PreprintCell Biology

Inflammation-driven reprogramming of goblet cells underlies the onset of serrated adenomas in colon cancer

Mathijs P. Verhagen, Emily Middendorp Guerra, Rosalie Joosten, Andrea Sacchetti, Wenjie Sun, Karishma A. Lila, Alex L. Nigg, Eiman I. Ahmed, Heba Saadeh, Thierry P. P. van den Bosch, Wouter Hendrickx, Jessica P Roelands, Annemarie C. de Vries, Michail Doukas, Riccardo Fodde

The paper investigates how inflammation reprograms goblet cells into tumor-initiating cells in colon cancer using single-cell RNAseq and mutation spectrum analysis.

bioRxiv · Jun 23, 2026 · PreprintCancer Biology