BiochemistryNature CommunicationsPeer-reviewed
GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome
Alžběta Roeselová, Sarah Maslen, Jessica Zhiyun He…·David Balchin
This study investigates how GroEL/ES interacts with nascent proteins on ribosomes, showing that GroEL binds and destabilizes substrates, while GroES facilitates partial encapsulation and refolding.
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