Ryan Hisner

This study shows the QTQTX motif in BA.3.2 S protein is not required for cleavage or lung cell entry, which depends on TMPRSS2 instead.

The paper analyzes over 3000 SARS-CoV-2 sequences from chronic infections to identify mutation patterns linked to viral persistence and long Covid.

This study identifies recurrent saltational events in SARS-CoV-2 evolution, linking them to persistent human infections rather than zoonotic sources.

This study finds that young children have lower neutralizing antibody titers against BA.3.2.2 compared to adults, despite similar titers against dominant variants, suggesting age-related differences in susceptibility.

The paper shows that mutations increasing ORF9b expression are common in SARS-CoV-2 variants and PCI sequences, suggesting ORF9b's role in viral evolution and immune evasion.