Andrew Ward

This study shows Grb10 regulates fetal growth independently of Igf1r and Insr, with some organ-specific interactions, particularly in the liver.

This study generates Grb7 KO mice and shows Grb7 and Grb14 have minimal impact on fetal growth but Grb7 may promote kidney growth and subtly affects glucose metabolism in adults.

This study shows that mice lacking paternal expression of Grb10 exhibit increased risk-taking behavior in specific tasks, supporting the idea that imprinted genes influence risk tolerance oppositely based on parental origin.

The paper shows that mice lacking paternal Grb10 make fewer impulsive choices, suggesting imprinted genes influence impulsive behavior and may contribute to pathological conditions.