Author

Ke Chen

University of California San DiegoORCID 0000-0001-8357-3741Unclaimed ORCID profile · follow to get notified of new preprints

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Ke Chen5 papers · BGI Research

Biology Disciplines

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Systems Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ChIP-seq· 2 Organism:E. coli· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:protein structure· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Bernhard Ørn PalssoniD· 3 shared Anand V. SastryiD· 2 shared Jonathan M. MonkiD· 2 shared Ye GaoiD· 2 shared Byung‐Kwan ChoiD· 1 shared Daniel QuachiD· 1 shared Donghyuk KimiD· 1 shared Edward CatoiuiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersSystems Biology

Bernhard Ørn PalssonORCID

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3 papers

Recent·Most cited

Unraveling the functions of uncharacterized transcription factors in Escherichia coli using ChIP-exo

Ye Gao, Hyun Gyu Lim, Hans Verkler, Richard Szubin, Daniel Quach, Irina A. Rodionova, Ke Chen, James T. Yurkovich, Byung‐Kwan Cho, Bernhard Ørn Palsson

This study identifies and characterizes 34 new DNA-binding transcription factors in E. coli, predicts their functions, and expands the known total number of TFs.

Nucleic Acids Research · Aug 11, 2021Peer-reviewedSystems Biology

Reconstruction of Fur pan-regulon uncovers the complexity and diversity of transcriptional regulation in E. coli

Ye Gao, Ina Bang, Yara Seif, Gayoung Nam, Anand V. Sastry, Ke Chen, Jonathan M. Monk, Kumari Sonal Choudhary, Sang Woo Seo, Eun Yeol Lee, Donghyuk Kim, Bernhard Ørn Palsson

The paper reconstructs the Fur pan-regulon in E. coli strains, revealing core, accessory, and unique regulons and their functional diversity.

bioRxiv · May 21, 2020 · PreprintSystems Biology

ssbio: A Python Framework for Structural Systems Biology

Nathan Mih, Elizabeth Brunk, Ke Chen, Edward Catoiu, Anand V. Sastry, Erol S. Kavvas, Jonathan M. Monk, Zhen Zhang, Bernhard Ørn Palsson

The paper introduces ssbio, a Python framework for integrating structural biology data into genome-scale systems biology workflows.

Bioinformatics · Feb 9, 2018Peer-reviewedSystems Biology