Shujia Zhu

The paper characterizes GluN3A-containing NMDARs as glycine-only excitatory glycine receptors, revealing their distribution, assembly, and unique gating mechanism.

The paper reports cryo-EM structures of NMDA receptors with GluN2C and GluN2D subunits, revealing structural and functional differences in their gating mechanisms.

The paper identifies YY-23, a compound that inhibits GluN2D-containing NMDARs in GABAergic interneurons, showing antidepressant effects in animal models.

This paper demonstrates whole-brain in vivo base editing in mice to reverse autistic-like behaviors by correcting a mutation in the MEF2C gene.