Bernd Fakler

The paper identifies a presynaptic core-module composed of Neurexins, T178 tetraspanins, and PTPRs that organizes synaptic adhesion and signaling in the mammalian brain.

The paper maps the human mitochondrial complexome at super-resolution, revealing protein complexes, networks, and interactions involved in mitochondrial function and disease.

The paper characterizes GluN3A-containing NMDARs as glycine-only excitatory glycine receptors, revealing their distribution, assembly, and unique gating mechanism.

This study identifies TMEM9 and PI(3,5)P2 as regulators of ClC-3 activity through cryo-EM structures showing TMEM9 blocks Cl- ion flow and PI(3,5)P2 stabilizes their interaction.

This study shows that APP17, a peptide derived from APP, does not regulate GABAB receptor activity in heterologous cells or neurons, suggesting sAPP acts through other receptors.

The paper identifies KChIP4a as a biophysical regulator that selectively affects inhibitory integration and learning in dopamine neurons projecting to the nucleus accumbens core.