Andrés Ruiz‐Linares

Clotting factor genes are associated with preeclampsia in high altitude pregnant women in the Peruvian Andes

This study identifies clotting factor genes PROZ, F7, and F10 on chromosome 13 as associated with preeclampsia in high-altitude Andean families.

Disentangling signatures of selection before and after European colonization in Latin Americans

This study identifies loci under selection in Latin American admixed populations, distinguishing between pre- and post-admixture selection, and finds signals related to immunity and energy metabolism.

Prediction Of Eye, Hair And Skin Color In Admixed Populations Of Latin America

The paper evaluates prediction accuracy for eye, hair, and skin pigmentation in admixed Latin Americans using genomic and phenotypic data, finding that Random Forest and regression perform best, and that pigmentation SNPs improve accuracy, especially for skin color.

Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates

This study examines genetic risk for bipolar disorder in extended families, finding that both common and rare variants contribute to susceptibility, with no significant segregation of large-effect variants.

Novel genetic loci affecting facial shape variation in humans

This study identifies 24 genetic loci associated with facial shape variation in humans through GWAS and confirms 13 of them in a multi-ethnic cohort.

Latin Americans show wide-spread Converso ancestry and the imprint of local Native ancestry on physical appearance

The paper analyzes ancestry in Latin Americans using haplotype-based methods, finding widespread Converso ancestry and links between Native ancestry and facial features.

Understanding the Hidden Complexity of Latin American Population Isolates

The paper analyzes genomic diversity in Latin American population isolates, finding increased genetic diversity and consanguinity compared to the Finnish isolate.