Garrett Hellenthal

The paper identifies systemic epigenetic variants linked to periconceptional environments in human fetal development, finding more variants in Black Americans and associations with cancer and neurodevelopment.

This study sequenced ancient and modern genomes from the Ryukyu Archipelago to show genetic differentiation between Ryukyu Jomon and Hondo populations, with admixture occurring around 1,000 YBP.

The paper links KZFP-mediated DNA methylation of a primate-specific transposon to type 1 diabetes risk through genetic and epigenetic analyses.

The paper examines negative selection on baboon admixture, finding stronger selection on the X chromosome in Tanzanian and Ethiopian populations.

ASAP uses PCA and NNLS to reliably estimate ancestry in admixed individuals, even with high missing data, and performs faster than existing tools.

The paper analyzes population genetics in the Eastern Highlands of Papua New Guinea using genome-wide data, revealing genetic structure, admixture events, and evidence of female-biased migration linked to the kuru epidemic.

Ancient DNA from 181 North Eurasian foragers traces a stable west-to-east ancestry gradient and ties Yakutia_LNBA ancestry, with Y-haplogroup N, to Uralic speakers and Seima-Turbino metallurgy.

The paper shows genetic effect sizes are similar across African and European populations for most traits, suggesting shared causal mutations and improving GWAS portability.

fastGLOBETROTTER identifies, dates, and describes admixture events using haplotype information, revealing new admixture signals in European populations.

The paper identifies hypervariable DNA methylation sites across multiple tissues and ethnicities, showing they are influenced by environmental factors and established early in human development.

This study identifies loci under selection in Latin American admixed populations, distinguishing between pre- and post-admixture selection, and finds signals related to immunity and energy metabolism.

The paper identifies shared post-admixture adaptation patterns in the Americas by analyzing genomic data from 6,000 admixed individuals, highlighting regions associated with immune response and disease traits.

This paper introduces methods to infer population histories using ancient genomes and genealogies, revealing insights into population dynamics and mutation rates in ancient populations.

The paper analyzes genomic data from Indigenous groups in Panama to reveal pre-Hispanic demographic changes and the genetic structure of the Isthmo-Colombian area.

This study examines the genetic structure of Ethiopians, linking cultural and geographic factors to genetic diversity and intermixing across 68 ethnic groups.

This study analyzes the genetic impact of European colonization on the Americas using genome-wide data from 12,000 individuals, revealing complex contributions from European, African, and other sources.

The paper analyzes the genetic structure of modern-day Italians to reveal ancient and archaic ancestries shaping Southern European populations and Neanderthal DNA distribution.

The paper analyzes ancestry in Latin Americans using haplotype-based methods, finding widespread Converso ancestry and links between Native ancestry and facial features.

This paper uses haplotype-based methods to reveal genetic structure in Ireland, showing regional diversity and historical migrations, with implications for genetic association studies.

This study analyzes genetic data from Zoroastrians in Iran and India to explore population structure, gene flow, and selection, revealing patterns of endogamy, admixture timing, and disease-related selection.

This study shows early European farmers descended directly from Neolithic Aegeans, linking Mediterranean and Central European farmers to southwestern Asia.