Deshka S. Foster

The paper constructs a pan-cancer single-cell atlas to improve tumor identity inference and identify genetic vulnerabilities by integrating high-quality malignant cells across multiple cancers.

This study uses single-cell and spatial transcriptomics to identify distinct tumor states in uterine leiomyosarcomas and proposes drug targets based on these states.

The paper uses integrated spatial multi-omics to study fibroblast fate during tissue repair and defines mechanisms controlling cell fate in wound healing.