Author

Winiffer D. Conce Alberto

Harvard UniversityORCID 0000-0002-4097-9861Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:CITE-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Andrea GarmillaiD· 2 shared Blake E. SmithiD· 2 shared Caleb R. PereziD· 2 shared Connor S. DobsoniD· 2 shared Ellen J.K. XuiD· 2 shared Michael E. BirnbaumiD· 2 shared Michael Lawrence DouganiD· 2 shared Qingyang Henry ZhaoiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Andrea GarmillaORCID

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Author profile →

4 papers

Recent·Most cited

Activation-dependent lentiviruses enable antigen-specific T cell expansion and transduction

Blake E. Smith, Lindsey M. Draper, Andrea Garmilla, Caleb R. Perez, Nishant Kumar Singh, Lucia T. Padilla, Ellen J.K. Xu, Stephanie A. Gaglione, Jiao Shen, Winiffer D. Conce Alberto, Qingyang Henry Zhao, Connor S. Dobson, Kole T. Roybal, Michael Lawrence Dougan, Michael E. Birnbaum, Stephanie K. Dougan

This paper develops 4-1BB-targeting lentiviral vectors to selectively expand and transduce antigen-specific T cells, enhancing their function in cancer immunotherapy.

bioRxiv · May 13, 2026 · PreprintImmunology

Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells

Ellen J.K. Xu, Blake E. Smith, Winiffer D. Conce Alberto, Michael J. Walsh, Birkley S. Lim, Megan T. Hoffman, Qiang Li, Ariana E. Barreiro, Emma N Finburgh, Jiayi Dong, Andrea Garmilla, Qingyang Henry Zhao, Caleb R. Perez, Stephanie A. Gaglione, Connor S. Dobson, , Michael E. Birnbaum

This study develops pMHC-targeted retroviruses for in vivo gene delivery to tumor-specific T cells, enhancing their expansion and anti-tumor activity in mouse models.

Science Advances · Nov 7, 2025Peer-reviewedImmunology

HIV Diversity Considerations in the Application of the Intact Proviral DNA Assay (IPDA)

Natalie N. Kinloch, Yanqin Ren, Winiffer D. Conce Alberto, Winnie W. Y. Dong, Pragya Khadka, Szu-Han Huang, Talia M. Mota, Andrew Wilson, Aniqa Shahid, Don Kirkby, Marianne Harris, Colin M Kovacs, Erika Benko, Mario Ostrowski, Perla M. Del Río Estrada, , Richard Brad Jones

The paper evaluates the Intact Proviral DNA Assay (IPDA) for HIV reservoir quantification, finding that HIV diversity leads to a 28% failure rate and underestimation of reservoir size.

Nature Communications · Jan 8, 2021Peer-reviewedGenetics

Heritable variation in resistance to the endonuclear parasite Holospora undulata across clades of Paramecium caudatum

Jared Weiler, Giacomo Zilio, Nathalie Zeballos, Louise Solveig Nørgaard, Winiffer D. Conce Alberto, Sascha Krenek, Oliver Kaltz, Lydia J. Bright

The paper investigates heritable variation in resistance to the parasite Holospora undulata across Paramecium caudatum strains, finding substantial genetic variation and geographic patterns of resistance.

Frontiers in Microbiology · Dec 14, 2020Peer-reviewedGenetics