Author

Patrick M. Sullivan

Duke UniversityORCID 0000-0001-8402-2634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aishe Kurti· 1 shared Anil G. CashikariD· 1 shared Anna AmelianchikiD· 1 shared David M. HoltzmaniD· 1 shared Douglas F. CoveyiD· 1 shared Gregory A. PetskoiD· 1 shared Guojun BuiD· 1 shared James Doherty· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aishe Kurti

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintAug 31, 2020

APOE2 promotes longevity independent of Alzheimer's disease

Mitsuru Shinohara, Takahisa Kanekiyo, Masaya Tachibana…·Guojun Bu

This study shows APOE2 is linked to longer lifespan regardless of Alzheimer's disease, with preserved activity and lipid metabolism playing a role.

DOI 10.1101/2020.08.31.255141

humanbulk RNA-seq

𝕏 PostBluesky

NeuroscienceJournal of NeuroinflammationPeer-reviewedJun 17, 2020

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

Man Ying Wong, Michael Lewis, James Doherty…·Wenjie Luo

This study shows that 25-HC enhances IL-1β production in microglia, particularly in apoE4-expressing cells, suggesting a role in AD neuroinflammation.

121 citationstop 3%

𝕏 PostBluesky