Author

Aishe Kurti

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Guojun BuiD· 2 shared John Denis FryeriD· 2 shared Akhilesh PandeyiD· 1 shared Axel D. MenesesiD· 1 shared Benjamin J. MaddeniD· 1 shared Cassandra L. RosenbergiD· 1 shared Chia‐Chen LiuiD· 1 shared Cristine M. CharlesworthiD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Guojun BuORCID

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2 papers

Recent·Most cited

TREM2-H157Y Increases Soluble TREM2 Production and Reduces Amyloid Pathology

Wenhui Qiao, Yixing Chen, Jun Zhong, Benjamin J. Madden, Cristine M. Charlesworth, Yuka A. Martens, Chia‐Chen Liu, Joshua A. Knight, Tadafumi C. Ikezu, Aishe Kurti, Yiyang Zhu, Axel D. Meneses, Cassandra L. Rosenberg, Lindsey A. Kuchenbecker, Lucy K. Vanmaele, , Guojun Bu

This study shows that the TREM2-H157Y mutation increases soluble TREM2 and reduces amyloid pathology in mice, suggesting a potential protective effect against Alzheimer's disease.

Molecular Neurodegeneration · Jan 31, 2023Peer-reviewedNeuroscience

APOE2 promotes longevity independent of Alzheimer's disease

Mitsuru Shinohara, Takahisa Kanekiyo, Masaya Tachibana, Aishe Kurti, Motoko Shinohara, Yuan Fu, Jing Zhao, Xianlin Han, Patrick M. Sullivan, William G. Rebeck, John Denis Fryer, Michael G. Heckman, Guojun Bu

This study shows APOE2 is linked to longer lifespan regardless of Alzheimer's disease, with preserved activity and lipid metabolism playing a role.

bioRxiv · Aug 31, 2020 · PreprintNeuroscience