Charles H. Schleifer

This study shows ketamine broadens neural spatial tuning and impairs spatial working memory in healthy humans, linking NMDAR antagonism to cortical microcircuit disruptions.

The paper identifies neurotransmitter systems linked to specific symptom dimensions in early psychosis using neuroimaging and PET data.

This study identifies genetic maps of human sulcal complexity using rare and common variants, revealing new mechanistic pathways for cortical morphogenesis.

This study compares cerebellar volume changes in 22q11.2 deletion and duplication carriers, finding divergent structural and behavioral associations.

The paper identifies a transdiagnostic functional connectivity pattern in early psychosis linked to cognitive inflexibility and arousal dysregulation across different diagnoses.

This study investigates developmental dysconnectivity in 22q11.2 deletion syndrome using a cross-species approach, finding age-specific fMRI connectivity changes with synaptic origins.

The paper compares functional brain measures between 22qDel and CHR cohorts, finding distinct patterns of connectivity and variability disruptions.

The paper identifies a stable microstructural white matter signature associated with negative and somatic symptoms in early psychosis across two independent cohorts using PLS correlation.

This study investigates how ketamine induces distinct whole-brain functional connectivity patterns in individuals and links these patterns to gene expression and behavioral responses.

This study examines how 22q11.2 copy number variations affect subcortical brain volumes and their development across different age groups.

This study examines age-related changes in thalamocortical functional connectivity in 22q11.2 deletion syndrome and typically developing controls, finding altered developmental trajectories in specific networks.

The paper identifies brain-wide bi-directional connectivity alterations in cortico-striato-cerebellar circuits in schizophrenia using resting-state fMRI and validates findings with clustering and classification methods.

This study shows that LSD-induced changes in brain connectivity are mediated by the 5-HT2A receptor, as demonstrated by the blocking effect of a 5-HT2A antagonist.