Systems BiologybioRxivPreprint
Regulatory perturbations of ribosome allocation reshape the growth proteome with a trade-off in adaptation capacity
David Hidalgo, César A. Martínez-Ortiz, Bernhard Ørn Palsson…·José Utrilla
The paper shows that reducing ribosomal RNA operons or mutating rpoB in E. coli increases growth rate but reduces hedging functions and adaptation capacity.
DOI 10.1101/2021.08.01.454633