Author

Katharina Miria Kirchhof

Karolinska InstitutetORCID 0000-0001-8412-4585Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

André G. DeslauriersiD· 1 shared Ann-Charlotte BjörklundiD· 1 shared Dimitris C. KanellisiD· 1 shared Eirini P. PapapetrouiD· 1 shared Elli PapaemmanuiliD· 1 shared Eva Hellström‐LindbergiD· 1 shared Gabriele TodiscoiD· 1 shared Indira BarbosaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

André G. DeslauriersORCID

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1 paper

Recent·Most cited

Cancer BiologyLeukemiaPeer-reviewedAug 26, 2025

SF3B1-mutant mis-splicing of UBA1 confers a targetable therapeutic vulnerability through UBA1 inhibition

Jonas Thier, Sophia Hofmann, Katharina Miria Kirchhof…·Vanessa Lundin

This study identifies UBA1 mis-splicing as a therapeutic target in SF3B1-mutant myelodysplastic syndromes, showing that UBA1 inhibition sensitizes these cells to treatment.

4 citations

humanbulk RNA-seq

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