Indira Barbosa

This study compares proteomic profiles of steady-state and cultured human erythroid progenitors, revealing how culture-induced stress alters protein expression and erythroid maturation dynamics.

This study identifies how RNA splicing factor mutations drive myeloid neoplasm by disrupting proteomic networks through mis-splicing, validated via single-cell transcriptomics and proteomics.

This study identifies UBA1 mis-splicing as a therapeutic target in SF3B1-mutant myelodysplastic syndromes, showing that UBA1 inhibition sensitizes these cells to treatment.