Author

Brendan G. Dwyer

Stanford MedicineORCID 0000-0001-8593-4184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Nathanael S. GrayiD· 3 shared Bryan A. RomeroiD· 2 shared Gerald R. CrabtreeiD· 2 shared Hannah M. JonesiD· 2 shared Meredith Nicole Nix· 2 shared Stephen M. HinshawiD· 2 shared Tinghu ZhangiD· 2 shared Yanlan Wang· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Nathanael S. GrayORCID

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3 papers

Recent·Most cited

Cancer BiologyCellPeer-reviewedJul 20, 2026

A Bivalent Molecular Glue Linking Lysine Acetyltransferases to Oncogene-induced Cell Death

Meredith Nicole Nix, Sai P. Gourisankar, Kevin Bowman…·Gerald R. Crabtree

This paper develops KAT-TCIPs to induce cell death in diffuse large B cell lymphoma by redirecting p300 and CBP to activate programmed cell death genes repressed by BCL6.

17 citationstop 1%

humanChIP-seq

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Cancer BiologybioRxivPreprintNov 3, 2025

Design and Development of DNA Damage Chemical Inducers of Proximity (DD-CIP) for Targeted Cancer Therapy

Tian Qiu, Yeuan Ting Lee, Brendan G. Dwyer…·Nathanael S. Gray

This paper introduces DD-CIPs, bivalent molecules that induce DNA damage response and apoptosis in cancer cells, showing efficacy against PARPi-resistant cancers.

DOI 10.1101/2025.11.03.686423

humanproteomics

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BiochemistrybioRxivPreprintSep 25, 2024

Discovery of electrophilic degraders that exploit SNAr chemistry

Zhe Zhuang, Woong Sub Byun, Zuzanna Kozicka…·Nathanael S. Gray

This study develops electrophilic degraders using SNAr chemistry, enabling selective protein degradation without requiring a defined E3 ligase recruiter.

9 citations

experimental assaydrug response / drug discovery

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