Developmental BiologyCell stem cellPeer-reviewed
Enhancing Sox/Oct cooperativity induces higher-grade developmental reset
Caitlin M. MacCarthy, Guangming Wu, Vikas Malik…·Sergiy Velychko
This study identifies a Sox2 mutation that enhances Sox/Oct cooperativity, improving iPSC reprogramming efficiency and enabling reprogramming of aged cells across species.
38 citations