Jason C. Wester

The paper investigates synaptic connectivity and physiology of dendrite-targeting interneurons in hippocampal CA1, revealing cell-type-specific circuits between deep and superficial pyramidal cells.

This study shows that SATB2 is required for superficial pyramidal cell differentiation and biased feedforward inhibition in CA1 hippocampus by suppressing PV+ interneuron synapse formation.

This study shows that adult hippocampal NSPCs secrete VEGF, which supports and protects hippocampal function independently of neurogenesis.

This study shows that Arid1b haploinsufficiency in inhibitory interneurons leads to cell-type-specific synaptic and developmental changes in ASD.

This study shows that Arid1b haploinsufficiency in excitatory neurons alters membrane properties and synaptic connectivity but does not cause social or seizure phenotypes.

The paper identifies cell-type specific transcriptomic signatures in mouse neocortical regions and links them to autism risk genes.